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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ae1b6b972bcfca033daf63ebfe61b9bc16beb5fff764c83bab64ff0277a0624' 
  AND token = 'HvA08pjSIA6LHjOiC/+lezzdAV6a7JledIrFRzRvuTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}