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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeed3784fd5a9d4e683be155f05a18b3ef959b7897cefec654f2c18a18e9ec44' 
  AND token = 'mYzUCLdrV+N3UY6/RF9wsFt5oNKmLXhvrCxoL/XQkoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}