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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '382d28751086e19a9414db8e57b2f1274d7127fba40a36c28afaee0835e12ca8' 
  AND token = 'dMeUWXJRUJmoo9W7QLyBWFo1l2CQt3SX81ea0vogzqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}