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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c77c06ca07e64698f349da6a172e03ccbbda732a4cc898dab8bb87a8bd3f693d' 
  AND token = 'yNDz49b1KVNGXEjIL8KsKrpW784TTuCoRIowu8ER0vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}