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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aad6cb5c53e6e88e5754175cd2a4ab50475f4f09b28c3b09c63480e7d4c416b' 
  AND token = 'zXosn5hunixrutAcvBZJYhvivuynR/82xzklQulGKAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}