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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0be3dce525d449f446b42ecfcc01f6c7c21952b682b0f4f0b331d8496083121' 
  AND token = '69DaoYlmBueH2tFAB+GbagrNFUW56oFxMaUuv8kolnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}