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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d27d0902400e08d051c385861ec3771526ee7a86060baa4e3345610d447182' 
  AND token = 'T0tA2m8TsLt5tppuY6stfFKELB4RS3U1dVPRg5psxC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}