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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f050b3f843aaf270d219946afd23fb975b9f4912f8f8f8b413e0302fdbedb7' 
  AND token = '+PSHcUT+ZX2nww3fZBapYEvOqvgTeQmaYn5L+yWDRoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}