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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452c08f6fca9d210e1cc7d9c66d58109ad2d7c898ea8adb7bf5362e515da5fa3' 
  AND token = 'eVJCJiJvYSmzuFb1G1/b1KT9hzyAt6yBtromk4eLJLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}