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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e27d8add7fb01cd43694a6e47fde0b02fc3cd0ba1cc274473afa13b765fcb6a2' 
  AND token = 'MUVp2t3saeCqxq0JM3G49+r60pG1MHEP/nDLWgDcw9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}