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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45661e2fbc9bedb4208452e980c321ce30d0ada6521e7ae596e2ae89f9970aa' 
  AND token = 'm2PSB4VnGgNLh+RKI1YnehWUHky9F16GInPIDnfvADA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}