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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '008c956781153ce2743381bf3a1bc6d6c0a039979b49b57a08185dc8423c94aa' 
  AND token = 'Z00pnx4IcxAbgsw2e3Vhly/+0waMBnJKHl8qQbo1u4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}