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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372d8682e569a105de01a7a5c53c4f82ee6e09b6799554d6170e117174f33e21' 
  AND token = 'Ic2PUHUsKgCSZ3dTFutOJNFdL+GitSYFkp5LYKZc9kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}