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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52482953c79688ed1e1e0bff371bafb9df5cc96059bc6562bd311c26c3eca973' 
  AND token = 'TGS7SzPzSVGrtcxPOvT6oCTUDMwvtLsfkeu9cUSiZeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}