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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40b500864bccd53dceaf0d55a5715be54d2a74b1aaec758e2a5af144b8a21ef0' 
  AND token = '0DvUZkGuW1Rzro0XRiQSaQ+eQpjlgTBOQEY0hrwIgew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}