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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd597c9b28752627df070a3d9cc60d0f3897c67a3ff7d7ab9d5bcac1ee8e78206' 
  AND token = '4E+3dOkHeFny74OT5YwcdWb5pYmN4DHQzVSgLO0c9dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}