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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3454f4ba669a130d1d60240f5e6727cffd194586c67add41bb520e6e42982db8' 
  AND token = 'z2sdZsMGDL/rWL0V+k5Kpthd+0o+gcuzd5kwN6Sf0q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}