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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d63878f65a6c272d59fef6fc4bc3cafa63e42eadf197a8466f9a2064926a106' 
  AND token = 'n6QoX1B+xPsMN9bsBqXqH/riktHMbdqVfRqlBwATzxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}