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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a85bc631404963efd71f5ae6dbf77b727e843742a65d1d64467c3c87578ae1' 
  AND token = 'ypyqFTtv5qPK4x41TZNpaTgQScrNxL12S3K8bdZ6vMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}