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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5821df8a13894fca1a6844fe505f2845c6be900dcd1424cfcfb8aa146ab0f1dd' 
  AND token = 'LIB5+DLasvqZGnv75Wb5EvKAXq0HhBMC9JTAYEkEk/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}