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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b5bef98f98c7b5500178224dc0c5a211b34d2a05c6df1d06944bd2d55ac8fd4' 
  AND token = 'PUW1MdvnbhpTMXRO5tWdvMPP5DDs5guIs/QIv7vggdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}