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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a9b06a4e6b158acd7ee59fc5af6b10fef7210ef69bec879a5c042e3b9260f2' 
  AND token = 'Pc5Puu/j0msCGxt3Zx3qn9iMVxi/2aCkuZ5CCXMZeC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}