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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c065cd6ad0a51dd59b33b138b269888c98d6b4b1277c2c17787229ccb67a6b0' 
  AND token = '9DrCMDDcrKH04OC0D/mzYDjTcMnbXMnb5fLz0/ZVd8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}