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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '548a8cb204094c1bc91371b0177b9d8537e5e71e888a23117733934117148f91' 
  AND token = 'Zdqy6EW+YXXka0dMMMCPPsxhB9IBFIiYzO9nHKvMFp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}