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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '248ca9b94fa5bfd26eeaf234489198c4c2147cff8fdb1ab8c8b4030051f1582f' 
  AND token = 'I4kFWuNe4XH817tlDweEv+qfaKVz+63vN/xhf3FJdOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}