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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21da5ec03f1645e2eb7e7fc3bfb1cfac96cdcc29b9270152b955dbedd00546c4' 
  AND token = 'qjoyhtB2PbjQ3aGLxS4l/ThXDubsBpu7+aYvv/QRB6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}