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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4416b3121a1d8fe0b593ddb7b0faf6770c238b20b1bb52ddc581840155f1a11' 
  AND token = 'QbgHpqp/c13HjYpf1hfpemFdjgSz1yWLu1q1qlQ7c5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}