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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c3c733ddf542c584dbba31f9852dbb60e8ec4b6a135bf0843378961c497dfbf' 
  AND token = 'UwlVHI6el6dcu9tAdmfPi4a4dcjEqoMZ4MiV3FTIqYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}