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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99ce83c42d2dfee74fdb4bda9d3412280fd157b58acfd127abf9caafbb092145' 
  AND token = 'mNUuYQDmleej6vzVF7QD/UbxObhUgPe81dDZIn/9Z8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}