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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53da2f436298646ace94bcc08d39249759a992fe36128aec8bfbdf51eb518c9f' 
  AND token = 'Xro9YqHiHc01udTocE+6ma5879IFbjkG2+Ex9qkOZOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}