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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '545bb033e1347146bb21b02729952a1231019173c573c7ebdc270b7ade9d7c50' 
  AND token = '7+/zguSbRTVSF+sytu3b1saZ2GG/EP5AfMfvhQA4+b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}