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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372c0fa6e38f05eeb191c14bc649f2529b67f05bee221eff623be508b81ed06b' 
  AND token = '4F1PnzyGIR87ITni8E/7bO1e8JIsGTvn+v0RfbzFeJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}