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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e4e26d0b71431e70e4e255fb4f10b22536c3b999fe0d94e77f637fb6ebb5519' 
  AND token = 'YMhOiD+PHCDMC2w7Nsr7yNPUTW0wRuBO89g1rngC3hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}