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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7770e4c4fde2fbca726e21ec78b88bcf58f6b5c3d16788c74311cde4f6d07980' 
  AND token = 'sskm+CEEjIq2DsuH8JLEPP0YXxcxW7cz4hIlPc1ltCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}