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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e0310a92d91ad6b793aaf585865744e250a0757d1523a758f32f80d41db99a' 
  AND token = 'nhvnVm6N9/v2MJmaPdoyr35L2aP+aWeObKuT5+CDvc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}