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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10d85a15a457ed42cb4062cb19402ebcfd33b97b92517b38921632722a87d21f' 
  AND token = 'GOzMfw1U2RVH8S+wpdVAUWUerMdGCR79QQvjdmdSuMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}