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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad3a2a4faaaf8e2cdfdaaf560480c4c261fa4a5108b0d9bfac468eb3ad727615' 
  AND token = 'jHwAMtLBwAK4xfLQ1CyR0d09NS5iLDdu+xIqkwvgb3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}