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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f759da13727d0029e4479b70abd9273e157c5fd5571fc10dc0138e096b8d4ec' 
  AND token = 'm20dATZHCfg+rZSkKxDEfS8cvd0NMscjgaICNo4e3S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}