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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da48d2680098e9636bf378d81fb3b74bf0879a57fba9922cf3c3c078a17b2aed' 
  AND token = 'E6oOvqQNzyhpiJx8ZxktMbuM41u8Th1WylfJSN5inSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}