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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8354ee7c2d9dbb84604db3f34931689be687970b67c2a34003bd1b7fafb46aeb' 
  AND token = 'SJqn2N9syyR1Fn74uoYmnMqFe4aTEeeUWHtoZqkr+4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}