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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e586d0743d0fe6ffe16359e097804f08a95be4e5ec5997b303f31f807f95f49' 
  AND token = 'd1i5sQ+sM4S3PGq//TkbC/FaHSFazGbE6yb231ZnP+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}