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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afce9401025a2b900441085271ddc30e71b8e0db5aca593468abf8c0d532499c' 
  AND token = 'NrH+v6Gad0sWrRF3Ng+WFm3CmRoLdFHq9Kcz2d4Asj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}