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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c6dfe0c913b21aca9037593fbcb45f3849eb9cfc3a7ee7175c9825deeeeae39' 
  AND token = 'Lozcn9WROVd46T+KL02KynzGljRFwhu4N4AeruI+Nr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}