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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecff6d4b251a2a61563a4080fa429d7d225fc7fc09959ddef89d912660fe9214' 
  AND token = 'nd/N1wHIfzvSbJX400SjI9GB92vz0gVieYaB75H5eYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}