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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99bb6b2fe148e01270409894f380f3bbb036081ba8374ea9c15eb7aff1dc262d' 
  AND token = 'kOkVByoibw5NS1aQAbOgwZlTTQ7bGpKjNbFb+eyO8Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}