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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d0e244cd98705a4d09aa1c656acac8cf1b3cab2c1cc39bbb55aff5b6f9c51a3' 
  AND token = '2X8lgDj9pvhWlmme0GhXUdg0uhQc1qKhr8v86w40ghA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}