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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f1c62a152079583cfedfebd7db6e733e9ec9109413eae52485932288fcd7a8' 
  AND token = 'EDVA8JP6JOAWxr/kbx1Lk0QhzrjEFzBW7JnUf3Mpe/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}