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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '927a317db85994b9eea3e792054654c1c24cc34fea5f70c9c67e0affd650bfc2' 
  AND token = '22Vb6DQeYMi1aD9z0JeaaMtY7TzrfsjjB2u0dBYqvoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}