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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c60cccd407ea40a98282c2b6a50d5ef016d75bed23e2231b685c2394d4bd59b' 
  AND token = 'bYN62ycDznk14+Fbkiv8Pe+hgCIo5JS3KqGlf0r9ZWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}