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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6b4757bbddb17088f3af575ab1e8827a5f2444b9d604ba636a9eb79fa0316a' 
  AND token = 'uXKD1b3czlfm8nntZHBob3tLlIg0lumqmAzqiuAyBZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}